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ZBIO

Requested read · Saturday 22 August 2026, 12:41 · same framework and thresholds as the weekly CFO screen

Market regime: SPY above its rising 200DMA; efficiency ratio 0.06 — overlapping, stand aside. Stage: Mature Trend.
ZBIO
Zenas BioPharma, Inc.
Early Trend Expansion, sector confirmed; strongest on sponsorship (19/20); weakest on insider signal (12/20). Last earnings absorbed (-6.7%); 3 insiders buying.
Early Trend Expansion XLV sector confirmed no CFO purchase$7,671,338 other insiders (6) 3 insider(s) net purchase ratio +1.00 buy date unknown
80
conviction / 100
85.8
technical / 100
$40,000–$50,000
Press
Regime clarity17.9
Sponsorship / positioning19.1
Volatility behaviour16.0
Catalyst alignment (insider)11.5
Cross-asset confirmation15.6
Last
32.29
Add above
33.08
Cut below
27.81
50DMA
28.08
200DMA
26.05
ZBIO daily chart: price with 50 and 200 day moving averages, volume, and on-balance volume
ZBIO — daily, 14 months
XLV sector ETF daily chart
XLV — sector ETF, daily, 14 months
Pillar detail, thesis support and invalidation
Regime clarity
  • price above 200DMA
  • 200DMA rising
  • 50DMA rising
  • partial HH/HL structure
  • efficiency ratio 0.27
Sponsorship / positioning
  • OBV 50d slope +0.188 avg-daily-volumes/bar
  • price/volume history is NOT one continuous security — a single 52% session gap. A conversion, large secondary or stock merger changes the share count, so the 200DMA averages two capital structures and OBV sums two different securities. Read this pillar with suspicion.
  • no OBV divergence at highs
  • OBV flat-to-rising through last pullback
Volatility behaviour
  • last pullback 11.0% deep
  • no wide downside expansion bars (30d)
  • ATR expanding vs 20d mean
Catalyst alignment (insider)
  • cluster: 3 distinct insiders buying (3 CEO, 3 Director)
  • net purchase ratio +1.00 (3 buying vs 0 selling)
  • NO CFO purchase in the window — the CFO-specific terms score zero
  • other insiders bought $7,671,338 (3 CEO, 3 Director) — counted through cluster breadth and net buying only
  • no CFO buy to date — recency not scored
Cross-asset confirmation
  • closest sector ETF: XLV
  • XLV above rising 200DMA (sector-led)
  • XLV vs SPY 6m: +0.6 pts
  • stock vs XLV RS (3m/6m avg): +28.4 pts
What strengthens the thesis
  • A confirmed higher high above 33.08 on expanding OBV.
  • Pullbacks that hold the rising 50DMA with flat-to-rising OBV.
  • XLV extending its own trend while the stock holds relative strength.
  • Continued base-building above the reclaimed 200DMA without volatility expansion.
What invalidates the thesis
  • Loss of the rising 50DMA (28.08) with expanding volatility — reduce.
  • Breakdown below the prior structural base (27.81) — exit, no averaging down.
  • OBV divergence during a price acceleration — reduce.
  • Sector ETF losing its own 200DMA — remove capital regardless of stock behaviour.
Insider detail
  • CFO: —
  • 0 CFO purchase(s), $0 total; last filed 2026-05-18 21:12:28
  • Market cap $2,104,556,416 · 20d avg dollar volume $23,965,547
Net insider activity
Net buying across the insider group.
Open-market purchases$7,671,338
Open-market sales$0
Sales after option exercise$0
Distinct buyers / sellers3 / 0
Net purchase ratio+1.00
Net purchase ratio, excl. option-exercise sales+1.00
Purchase tape
No CFO purchase here — 6 purchase(s) by other insiders worth $7,671,338. These count toward cluster breadth and net buying, not the CFO-specific terms.
Trade dateInsiderSharesPriceValuePrice now vs buy
30 Mar 2026Moulder Leon O JrCEO54,000$18.91$1,021,140+70.8%
31 Mar 2026Lu HongboDirector3,768$18.63$70,198+73.3%
31 Mar 2026Fairmount Funds Management LLCDirector150,000$20.00$3,000,000+61.5%
31 Mar 2026Lu HongboDirector75,000$20.00$1,500,000+61.5%
28 Apr 2026Moulder Leon O JrCEO60,000$17.79$1,067,200+81.5%
18 May 2026Moulder Leon O JrCEO60,000$16.88$1,012,800+91.3%
Reaction to news
7 material events; 5 taken well, 0 badly; last earnings 13 Aug: absorbed (-6.7%).
SessionFilingEventGapDayvs SPYVol+5dRead
13 Aug 268-K · earningsResults of operations (earnings); Director or officer change-2.9%-6.7%-7.4%1.3x+8.3%Absorbed
13 Aug 2610-QQuarterly report-2.9%-6.7%-7.4%1.3x+8.3%Absorbed
13 May 268-K · earningsResults of operations (earnings); Director or officer change+2.3%+4.0%+3.5%1.1x-1.9%Rewarded
13 May 2610-QQuarterly report+2.3%+4.0%+3.5%1.1x-1.9%Rewarded
31 Mar 268-KMaterial agreement; Material obligation created; Other material event+2.4%+7.3%+4.4%3.5x+6.7%Rewarded
16 Mar 268-K · earningsResults of operations (earnings)-2.9%-3.4%-4.4%0.9x-11.2%Neutral
16 Mar 2610-KAnnual report-2.9%-3.4%-4.4%0.9x-11.2%Neutral